Panadol Night

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500mg Paracetamol + 25mg Diphenhydramine hydrochloride

Panadol Night contains two active ingredients, Paracetamol which is an analgesic (a pain reliever which relieves aches) and antipyretic (reduces body temperature when you have a fever) and Diphenhydramine hydrochloride, an antihistamine with additional sedative properties.

What does it relieve?

Panadol Night provides night time relief when you have pain such as:

  • Headaches
  • Migraine
  • Backache
  • Rheumatic and muscle pain
  • Toothache
  • Period pain

It also temporarily relieves fever and aches and pains associated with cold and flu which causes difficulty in sleeping

What's the format?

Film coated caplets.

What are its features?

Panadol Night relieves night time pain so you can have a good night sleep.


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Age Dose How Often
12 - Adult 2 caplets 20 minutes before bed 2 caplets before bed time, do not take more than 10 consecutive nights.

Also available in:

Usage directions, ingredients and warnings

Before using Panadol Night be sure to check the product ingredients and directions for use, and make sure you are familiar with any warnings and precautions.

Learn more below.

Place caplet(s) in mouth and swallow with water.


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Active ingredients:

  • Paracetamol 500mg
  • Diphenhydramine hydrochloride 25mg


  • Do not exceed stated dose.
  • Do not take more than 2 caplets per night
  • Do not take for more than 10 consecutive nights without consulting a doctor.
  • Other products containing paracetamol may be taken during the day but the total daily dose of paracetamol must not exceed 4000mg (including this product) in any 24 hour period.
  • Further doses of paracetamol should not be taken within 4 hours of a dose of Panadol Night

WARNING: May cause drowsiness. If affected, do not drive or operate machinery.

Do not take if you have Hypersensitivity to paracetamol, diphenhydramine, or any other ingredient in this product

Should not be used with other antihistamine-containing preparations, including those used on the skin

Medical advice should be sought before use in:

Patients who have been diagnosed with liver or kidney impairment

Patients with epilepsy or seizure disorders, myasthenia gravis, narrow-angle glaucoma, prostatic hypertrophy, urinary retention, asthma, bronchitis and chronic obstructive pulmonary disease (COPD).

In patients with glutathione depleted states such as sepsis, the use of paracetamol may increase the risk of metabolic acidosis.

May increase the effects of alcohol; therefore, alcohol should be avoided

Concurrent use of drugs which cause sedation such as tranquillizers, hypnotics and anxiolytics may cause an increase in sedative effects therefore medical advice should be sought before taking diphenhydramine with such medicines

Avoid use with other antihistamine-containing preparations, including topical antihistamines and cough and cold medicines.

Use with caution with monoamine oxidase inhibitors (MAOIs) or within 2 weeks of stopping an MAOI

Use with caution with other drugs with antimuscarinic properties (e.g. atropine, tricyclic antidepressants

Use with caution in the elderly, who are more likely to experience adverse effects.

Avoid use in elderly patients with confusion.

If symptoms persist, medical advice must be sought.

Keep out of sight and reach of children.


If you would like any further information regarding Panadol products, please call our INFOLINE (Freecall) +973 16500404 - Gulf & Near East countries

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