Panadol Extra with Optizorb Formulation3

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500mg Paracetamol + 65mg caffeine

Fight tough pain with Panadol Extra  with OPTIZORB, a powerful pain reliever that combines paracetamol and caffeine with advanced technology for a faster dissolving tablet.

Whether it’s a nasty migraine headache or painful muscle aches that are holding you back, when you’re fighting against tough pain, Panadol Extra  with OPTIZORB can help.

Panadol Extra contains a combination of active ingredients – paracetamol and caffeine – to create a powerful pain reliever that is clinically proven to help fight five types of tough pain: migraine headache, tension headaches, period pain, muscle aches and dental pain.

In fact, Panadol Extra  with OPTIZORB are particularly good for headaches, since the use of caffeine increases the chances* of achieving headache relief,1, 2 while the OPTIZORB technology releases the active ingredients up to 5x faster.** 

This means that Panadol Extra with OPTIZORB can start working in just 10 minutes.

Learn more about Panadol Extra with OPTIZORB Formulation – including what’s in them and how to use them safely – below.

*In comparison to paracetamol alone.
**Compared to Panadol Extra without OPTIZORB technology.

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Dosage information3

Adults and children aged over 12 years can take 1-2 tablets of Panadol Extra with Optizorb Formulation (500mg Paracetamol, 65mg Caffeine) every 4-6 hours with water as required. Do not exceed the maximum of 8 tablets in a 24-hour period. Do not use for more than a few days at a time except on medical advice.1

Panadol Extra with OPTIZORB is not recommended for use in children aged under 12 years.1

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Age Dosage Frequency
12 years – Adult 1-2 tablets Every 4-6 hours with water as required (maximum 8 tablets in 24 hours).

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Usage directions, ingredients and warnings3

Before using Panadol Extra with OPTIZORB Formulation , be sure to check the product ingredients and directions for use, and make sure you are familiar with any warnings and precautions.

Learn more below.

Panadol Panadol Extra with OPTIZORB Formulation3 is easy to use. Simply place the tablet(s) in your mouth and swallow them down with water. 

See dosage instructions above, or consult the product label to determine the appropriate dosage for you.

Couple Of Women Drinking Coffee And Laughing

Active ingredients: each Panadol Extra with OPTIZORB contain paracetamol (500mg) and caffeine (65mg).

Panadol Extra Tablets do not contain gluten, lactose or sugar.


  • Always read the product label before use and do not exceed the recommended dose. 
  • Panadol rarely has side effects when taken at the recommended dose, however if you do experience any side effects as a result of taking Panadol Extra Tablets, stop use immediately and consult a healthcare professional.   
  • Panadol Extra with OPTIZORB contain paracetamol. You should not use them with any other products that contain paracetamol, as combining paracetamol-based medicines may lead to an overdose. Always read the product label on any other medication you plan to take in combination with Panadol before use, and consult with a doctor or pharmacist to check that it is safe to do so.  
  • Panadol Extra with OPTIZORB contain caffeine. Excessive intake of caffeine (e.g. coffee, tea and some canned drinks) should be avoided while taking Panadol Extra.
  • Note that each Panadol Extra with OPTIZORB contain parahydroxybenzoates (sodium methyl, sodium ethyl, sodium propyl), which may cause allergic reactions. Ask a doctor or pharmacist before use if you are unsure about whether or not you should take Panadol.  
  • Panadol Extra Tablets are not recommended for use in children aged under 12 years. Keep them out of sight and reach of children. 


1. Does caffeine trigger or treat headaches? National Headache Foundation. Accessed 20/04/21.
2. Paracetamol, aspirin and caffeine for tension type headache. Bandolier. Accessed 20/04/21.

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